Domperidone

Emma - posted on 04/01/2010 ( 17 moms have responded )

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After months of trying to pump, so I can provide for my 9 month son when he starts daycare, my doctor finally prescribed Domperidone to help increase my supply. I have tried every technique out there to increase my supply so I can pump, was even desperate enough to try formula (which my son hated).



What I am wondering, how long will it be before I see any results. My doctor said it depends on the woman, but I am curious as to the other mums who have successfully used Domperidone.

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Renee - posted on 04/02/2010

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This is from the Canadian Breastfeeding Foundation:

Domperidone-2

How long can I use domperidone?
When domperidone was being used for babies (and now that cisapride is off the market, it is being used again), it was common for the babies to be on the medication for several months. Since the amount of domperidone that gets into the milk is very small indeed, from the baby’s point of view, there should be no issue in the mother taking it to increase milk supply for several months. Our experience with this drug is that short-term side effects are very few and almost always very mild. Worldwide experience with domperidone over at least two decades suggests that long-term side effects also are rare. Some of the mothers in our clinic, breastfeeding adopted babies, have been on the medication for 18 months without any apparent side effects. As mentioned in handout #19a Domperidone-1, patients using domperidone for stomach disorders may be on it for many years. I hope you won’t need domperidone for very long, but if it’s necessary and helpful, stay on it.

How long does it take for domperidone to work?
It depends on the situation. In a situation where the mother had had a good milk supply, but it decreased for some reason (e.g. going on the birth control pill, see handout #25 Slow Weight Gain After the First Few Months), domperidone often works very rapidly to increase the milk supply. Often, within a day or two the mother is seeing a difference (and so does her baby). But this is not always so, and in many situations, it may take a week or more for the mother to start getting an effect. On occasion, we have had mothers only starting to get an increase in their milk supplies a month or more after starting to take it. Therefore, we generally recommended that the mother take the domperidone for at least six weeks in order to be sure whether it has worked or not.

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It took me maybe a week to really see results, but after a few days it was even different. I started them when my son was 3 months old, and we are still going strong at 6 1/2 months. I say go for it, it's been a Godsend for me.

Sophie - posted on 04/01/2010

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I noticed a difference after 24hrs. After two weeks, there was a big jump in my production. Sadly this only lasted a couple months for me and my daughter lost all interest in the breast and weaned herself off at 8 1/2 months and my milk really dried up then.

Kate - posted on 04/02/2010

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I work @ a veterinary clininc, and honestly them only thing I had ever heard it being used on was horses. I believe it works pretty fast for them. Also fenugreek a natural supplemnet is supposed to help with milk supply. But I would not use it with the medication.

Hong - posted on 04/02/2012

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Dear all, a word of caution, domperidone might have serious side effect on the infant. I am a midwife and RN with 14 years of experience in O and G, I love babies, I love kids, I also love to breastfeed my own kids. I had extremely low milk supply after I tried all sorts of ways. Even after LSCS, I breastfed my boy within an hour of birth, I followed feeding him on demand. After two weeks, I took maxolon 10 mg TDS for 1.5 months, I requested my Dr to give it to me and I told him that I would monitor the side effect. When my son was two months old, I discovered that I had postnatal blue, it was a very horrible feeling, I just felt empty, lonely, and scary. I told my family members and I threw away all my maxolon stock. Then I changed to domperidone. I took domperidone 10 mg one tablet TDS for 1.5 months, then I changed to two tablet TDS for 2 months. I realized my son had constipation, and I decreased my dosage to one tablet BD. I searched articles regarding domperidone and constipation, and there might be some link. When he was 7 months old, I stop taking domperidon. I suspected that it might harm my little one even there was less than 7 mcg domperidone in the breast milk per day.

Then later on, I discovered that my little one had vomitin problems and very long respiratory problems. I brought him to see pads almost weekly, but he still had a lot of phlegm. I searched again, then I went back to my pads, we started him on domperidone 1.5 mg BD and ranitidine 1.5 ml BD. He took them for 4.5 days. On day 5 of taking domperidone, I took oral erythromycin 500 mg for sore throat, I expressed my milk, only 60 ml, he took the breast milk in the afternoon. He was very quiet during the evening time, he slept through out the night, when I went for my AM duty, I saw that he moved a bit. Then in th morning, he had convulsion at home, than God, my mother in law quickly pinched his skin beneath the nose, and he was saved. My hubby rushed him to my work place, and I carried him to see a neuro pads. While waiting, he had another convulsion. Within few seconds, he lost conscious, I was so scared, but I quickly put him on the floor, used mouth to cover his nose and mouth to blow oxygen to him, and I instructed my families to shout for help. It was the most scary thing which happened to me. After few minutes CPR, shouting his name, ask God to help, ask evil to go away, I managed to bring my dear son back to me. Then the Neuro Paeds arrived at the most important time. He told me that there was pulse rate now and CPR not required. Then his color came back. After this critical life experience, I am very thankful that My son is with me. He is so cute and he is recovering now. His MRI, EEG, blood test are normal. Nowadays, I searched a lot regarding domperidone and convulsion, domperidone can cause convulsion in infant, HSA highlighted this in Jan to Apr 2008. MIMS states clearly that domperidone can cause adverse drug reaction to infant like convulsion or seizure, extrapyramidal symptoms especially when it is used with anti fungal medication or erythromycin. There is no life research data as it is inhuman to carry out this kind of research on infants. It was only based on reported cases. But how many of us will suspect that domperidone can cause life threaten situation? How many innocent parents will report? How many parents can deal with such a critical situation? As a mother and a nurse, I really want to alert parents, always take precaution, some familiar drugs might cause adverse drug reaction to the lovely infants and children, each child is the everything to their parents, I really wish all the children are safe and healthy. My lesson is a very painful lesson, but I still want to thank God that my son is safe and healthy now. I really hope that other parents can think few times before they take some medications to increase milk.

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17 Comments

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Krystal - posted on 03/17/2013

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I have literally taken 6 pills, and it has already started working... My boobs are huge and are killing me they are so full..... don`t know if its worth it or not but it certainly worked fast!

Vanj - posted on 07/09/2011

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Anyone who needs domperidone? I have 115 tablets of 30 mg each. I don't need them anymore. Pls email me at vanjbaquiran@aol.com if you want it. I will ship. I just don't want it to go to waste.

Amanda - posted on 04/09/2010

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In Canada it's common practice to prescribe domperidone. I asked my pharmacist and my doctor why I keep seeing things that say not to use it while breastfeeding. They both said they had never heard that. I did some reading on the internet and found out that reason the FDA freaked out about it is in large quantities, mainly intraveanously (and in cases when there is a pre-exsisting condition) it can cause adverse reactions in mothers and infants. It's also listed as the safest drug that can be used to increase breastmilk. If it has been prescribed by a doctor than they have obviously decided that the benefits far outweigh the risks and I will trust the decision of my doctor who actively practices medicine over the ones who are paid to sit on their butts and write for websites. More than once I have heard that the worst thing for modern medicine is all the "medical" websites.

Shelly - posted on 04/09/2010

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I took Domperidone for the entire time i breastfed my daughter ( 12 months ) as i had supply issues triggered by a retained placenta which affected my initial milk supply.
It only takes a few days to have a very full effect if your on the maximum medication. I took it 3 times a day and had excellent results. Once you have increased your supply you can drop one tablet at a time - say one tablet once a day and wait a few days and if your supply isnt affected you can stop taking that pill and then try reducing another tablet once a day but always do it slowly and make sure it doesnt affect your supply.
I used the tablets combined with other ways of encouraging supply that i learnt from this breastfeeding forum. This forum was what kept me educated and allowed me to do what i needed to do to continue breastfeeding. Take a look:
http://www.i-am-pregnant.com/encyclopedi...

Good luck :o)

Johnny - posted on 04/09/2010

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I've been on domperidone for 20 months now. It has worked very well for us, but when I have attempted to get off of it, my supply completely disappeared (very angry toddler!). I'm glad to read it is working for you. From what I understand, most moms only need to go on it for 2-3 months to see a permanent improvement. Good luck!

Renee - posted on 04/08/2010

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Congratulations on sticking with it and I'm glad it's working for you. Like I said before I've been on it for months and plan on staying on it until we're done breastfeeding because my milk supply is just not there without it.

Emma - posted on 04/08/2010

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Thank you all. I do appreciate the advice but this something I did not rush into. As I said before I had tried every other method known to naturally increase my supply, which included pumping after feedings for a bit, taking fenugreek and thistle tea, eating the right foods to increase my supply. However after months of trying none of this worked for me. Now I am taking domperidone and I am able to pump some for my son when he is in day care.

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Amanda, I think the point to Ana's post is that domperidone is not a drug to rush into without careful consideration. In Australia, it is recommended that domperidone to increase breast milk supply should only be dome under medical supervision, http://www.thewomens.org.au/Domperidonef... and I assume this is the case in the US also.

Amanda - posted on 04/02/2010

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Re; Ana Herrera's post, was there a point to that or were you really bored? Not to be a b**** or anything.







When I started taking it my doctor told me it would start working within a week, it took less than 24 hours before I noticed an increase. At the time I was lucky to get 10 oz of milk per day, now I pump aprox 30 oz. Good luck

ANA - posted on 04/02/2010

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GENERIC NAME: DOMPERIDONE - ORAL (dom-PAIR-eh-doan)
USES: This medication increases movement through the digestive system. It is used to treat symptoms of stomach disorders. It may also be used to prevent nausea and vomiting caused by certain medications. Due to safety concerns, this medication is not to be used by breast-feeding women to increase production of breast milk.

HOW TO USE: Take this medication by mouth as prescribed usually 30 minutes before meals and at bedtime. Do not increase your dose or take this more often than directed. Your condition will not improve any faster but the risk of side effects will be increased.

SIDE EFFECTS: Headache, dizziness, dry mouth, nervousness, flushing, or irritability may occur the first several days as your body adjusts to the medication. Trouble sleeping, stomach cramps, hot flashes and leg cramps have also been reported. If any of these effects continue or become bothersome, inform your doctor. Notify your doctor immediately if you develop: chest pain, slow/fast/irregular heartbeat, swelling of the feet or ankles, difficulty urinating, swelling of the breasts or discharge from the nipple in men or women, menstrual changes, sexual difficulties. If you notice other effects not listed above, contact your doctor or pharmacist.

PRECAUTIONS: Tell your doctor your medical history, especially of: history of breast cancer, allergies. Limit your intake of alcoholic beverages. This medication should be used only if clearly needed during pregnancy. Discuss the risks and benefits with your doctor. Domperidone passes into breast milk. Due to the potential risks to a nursing infant, breast-feeding while using this drug is not recommended. Consult your doctor before breast-feeding (see also Uses section). FOUND HERE http://www.medicinenet.com/domperidone-o...

Renee - posted on 04/01/2010

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It took me a couple of weeks but it works great. I've been on it almost since the birth of my daughter because of a low milk supply from the get go. Good luck!

Elisa - posted on 04/01/2010

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my doc put me on domperidone at 9 months, because my milk suppy became really low, and I was not ready to stop breast feeding. I saw a difference in about 24 hours as well, and after a week, it was like I just gave birth, once I drank too much water, and had to wake in the middle of the night to pump! Its great though, I've been storing milk for when my daughter is in daycare. Good Luck! I had no side effects

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