How long does it take for medicine to leave your breast-milk?

Vanessa - posted on 09/16/2010 ( 1 mom has responded )

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Should I pump and dump? or Should I flush my system with drinking lots of water? or Should I wait a number of hours? before breastfeeding my baby again? I just took Fluticasone Nasal Spray and researched whether I should have done so after the fact. [dumb i know] So it says that it gets into the breastmilk and should only be taken if absolutely necessary because it is known to cause adverse reactions to nursing infants. Please only experienced replies. I'm waiting forever on the pharmacist line and have called twice already and I'm getting no answer.

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Minnie - posted on 09/16/2010

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It can be scary trying to make a decision about taking a drug you need when you are breastfeeding.



Here is the entry from Dr. Hale's Medications and Mother's Milk (the most reliable source of medication and breastfeeding information):



"Virtually none of the drug is absorbed systemically. Absolute bioavailability of nasal spray (meaning what your body can use) is less than 2%.



It is not likely that milk levels will be clinically relevant even with rather high doses.



No effects have been reported in breastfeeding infants."



Drugs are considered effectively 'used up' when five times the length of the half life has passed. The half life for fluticasone is 7.8 hours. So after 39 hours the drug is effectively eliminated. However- as stated from the entry above, this drug is only very minimally absorbed systemically and only after rats taking extremely high doses of this drug secreted any in their milk.



Most sources of drug information will take the safest liability route. The drug COULD get into milk, but was only evidenced in lab rats taking very high doses of this drug.

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