Obstetric Cholestasis Second Pregnancy

Kristeen - posted on 06/28/2009 ( 5 moms have responded )




Hi everyone,

Just wondering if anyone who had Obstetric Cholestasis in their first pregnancy has gone on to have more children? If so, did Obstetric Cholestasis rear it's head again and were you more closely monitored because you had suffered Obstetric Cholestasis before?

My hubby and I are planning on another little one in the near future and I just want to be as prepared as possible for what I may have to go through.




Marcella - posted on 08/29/2010




I had Obstetric Cholestasis with my twins just 2 years ago. I read you have over 70% chance of having in future pregnancies.. and yes now I'm pregnant and 25 weeks today and last night I woke up and noticed I was itching my hand!!!! I almost jumped up and screamed it's BACK! But yeah it's not bad yet with the itching but I'm sure It'll get worse... sorry no good advice.. I guess it's just what happends and you go with it and try to make the best of it. Have'nt told my Dr yet so I'm also anxious to see if they will monitor more closely. I got induced last time at 36 wks. How bout you?

Aggie - posted on 09/09/2010




Hi there

I had Obstetric Cholestasis in my second pregnancy, which was 8 years after my first... I was lucky that with my second pregnancy, my midwife and specialist took me seriously! I was actually prescribed- ursodeoxycholic acid (URSO) to stabilise the liver function as well as Vitamin K for blood clotting (not very easy to get when they stop making it.... ).

At 32 weeks my LFT's crept up over the 200's (NOT GOOD) and I was hospitalised and given steroid injections to mature babies lungs- in case they decided to induce me early.

I also had to have bloods done twice a week and had high tech ultra-sounds done every couple of weeks..

On the UP:

The drugs (slowly but shorely) started to do their job-my results stabilised and I was sent home.

I was induced at 37 weeks (known as the safe period in this case) and had a very healthy baby girl. The labour went smoothl other than losing quite a bit of blood for which I was kept on a drip all night to assist my uterus in contracting...

The great thing about the URSO tablets was that they STOPPED THE ITCH and improved my liver function test result. They do cost a bomb ($199AU), but- you cant put a price on life!

I am happy to share more information if you are interested.



Brittany - posted on 04/07/2010




I had Obstetric Cholestasis with my first as well, and am kind of scared to try again :( Hope everything is going well for you!

[deleted account]

Hey. I'm only 11 weeks and have not had any symptoms yet, but I bet there are some stories on itchymoms.com that answer your question. Best of luck. I think the only way to handle it is to just try for another child if you think you should and force the doctors to monitor you closely if you are worried about the outcome. Follow your heart.


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[deleted account]

I had undiagnosed ICP in my first three pregnancies with only hand and foot itching (1989, 1997, 1999) it was not until I was constantly itchy all over with my 4th (2002) that I looked online and printed internet information and told my OB that I wanted to be tested for ICP. There was not much info out 10 years ago, but I did find itchymoms.com and delivered 4 healthy babies (first and last 4 weeks early, the other two full term) Ironically, 2 years ago...my gallbladder flared up and I started itching all over again. I grabbed my 10 yr old lab work and ran to the Drs. Sure enough my BA levels were super high again and eventually they found gallstones which lead to the removal of my gallbladder. The surgeon said that based on the size, some of those gallstones were at least 10 years old. Hmmm, thats when the ICP was really bad. Connecting the dots, maybe.

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